Perch has been designed to solve the problems freelance designers and agencies deal with every day.
I’ve been using a great compiler for Less and Sass recently, works seamlessly very fast and some great options for compression.
Koala is a GUI application for Less, Sass, Compass and CoffeeScript compilation, to help web developers to use them more efficiently. Koala can run in windows, linux and mac. http://koala-app.com/